Office: MRB 221
Phone: (970) 491-5531
Google Scholar: https://scholar.google.com/citations?user=Bix11zcAAAAJ&hl=en
- B.S., M.S. University of Jordan
- Ph.D. Colorado State University
Cancer arises from changes in basic cell functions. My research focuses on cellular alternations leading to cancer for a better understanding of its initiation and development. This information can help in creating and improving cancer treatments. The lab different projects focus on: Cell migration, adhesion and metastasis; Mitochondrial function and apoptosis; Cytoskeleton and related proteins; Cell cycle and Anti-tumor drugs screening. The same biological concepts are applied in the lab projects studying male infertility
- Characterization of a Human Neuronal Culture System for the Study of Cofilin-Actin Rod Pathology Biomedicines, 2023.
- A novel derivative of picolinic acid induces endoplasmic reticulum stress-mediated apoptosis in human non-small cell lung cancer cells: synthesis, docking study, and anticancer activity PHARMACIA, 3, 2021.
- Age of the donor affects the nature of in vitro cultured human dental pulp stem cells SAUDI DENTAL JOURNAL, 7, 2021.
- Cofilin and Actin Dynamics: Multiple Modes of Regulation and Their Impacts in Neuronal Development and Degeneration CELLS, 10, 2021.
- Synthesis, docking study, and in vitro anticancer evaluation of new flufenamic acid derivatives PHARMACIA, 2, 2021.
- Alu-repeat polymorphism in the tissue plasminogen activator (t-PA) gene, seminal t-PA concentration, and male fertility INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE, 8, 2020.
- Biological activity and apoptotic signaling pathway of C-11-functionalized cephalostatin 1 analogues STEROIDS, 2020.
- SYNTHESIS AND CYTOTOXIC ACTIVITY OF SOME NEW BIPYRAZOLE DERIVATIVES HETEROCYCLES, 2, 2020.
- Cetyl-alcohol-reinforced hollow fiber solid/liquid-phase microextraction and HPLC-DAD analysis of ezetimibe and simvastatin in human plasma and urine BIOMEDICAL CHROMATOGRAPHY, 2, 2019.
- Molecular Regulation of Cancer Cell Migration, Invasion, and Metastasis ANALYTICAL CELLULAR PATHOLOGY, 2019.
- Alu DNA Polymorphism of Human Tissue Plasminogen Activator (tPA) Gene in Diabetic Jordanian Patients Iranian biomedical journal, 6, 2019.
- Cephalostatin 1 analogues activate apoptosis via the endoplasmic reticulum stress signaling pathway EUROPEAN JOURNAL OF PHARMACOLOGY, 2018.
- The cellular and molecular effects of the androgen receptor agonist, Cl-4AS-1, on breast cancer cells ENDOCRINE RESEARCH, 3, 2018.
- Inhibitory effect of Taraxacum officinale L (Compositae) aqueous root extract on spermatogenesis TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH, 1, 2017.
- Anti-spermatogenic activities of Taraxacum officinale whole plant and leaves aqueous extracts VETERINARY RESEARCH FORUM, 2, 2016.
- Human chorionic gonadotropin cutoff value determined by receiver operating characteristic curve analysis is useful but not absolute for determining pregnancy outcomes MIDDLE EAST FERTILITY SOCIETY JOURNAL, 2, 2016.
- Novel Palladium(II) and Platinum(II) Complexes with a Fluoropiperazinyl Based Ligand Exhibiting High Cytotoxicity and Anticancer Activity In Vitro JOURNAL OF CHEMISTRY, 2016.
- Palladium(II) complexes incorporating phenylazo arylmethine ancillary ligands: Synthesis, spectral and antitumor activity ARABIAN JOURNAL OF CHEMISTRY, 2016.
- Screening for CYP2C19 Gene variants in a healthy Jordanian population TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH, 12, 2016.
- 2-deoxy-D-Glucose Synergizes with Doxorubicin or L-Buthionine Sulfoximine to Reduce Adhesion and Migration of Breast Cancer Cells. Asian Pacific journal of cancer prevention : APJCP, 8, 2015.
- Genomic integrity of the Y chromosome sequence-tagged-sites in infertile and Down syndrome Jordanian males. Andrologia, 7, 2014.
- Feasibility of collecting umbilical cord blood in jordan and the effect of maternal and neonatal factors on hematopoietic stem cell content. Mediterranean journal of hematology and infectious diseases, 1, 2014.
- Non-overlapping activities of ADF and cofilin-1 during the migration of metastatic breast tumor cells. BMC cell biology, 2013.
- Dandelion (Taraxacum officinale) decreases male rat fertility in vivo JOURNAL OF ETHNOPHARMACOLOGY, 1, 2011.
- Microtubule remodelling is required for the front-rear polarity switch during contact inhibition of locomotion JOURNAL OF CELL SCIENCE, 15, 2011.
- Total body glutathione depletion induces oxidative stress and disrupts the immune function in mice TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY, 1, 2011.
- 2DG enhances the susceptibility of breast cancer cells to doxorubicin CENTRAL EUROPEAN JOURNAL OF BIOLOGY, 6, 2010.
- Prevalence and risk factors for anabolic-androgenic steroid abuse among Jordanian collegiate students and athletes. European journal of public health, 6, 2008.
- Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopenia BLOOD, 7, 2007.