LUBNA Tahtamouni Visiting Professor

Office: MRB 221

Phone: (970) 491-5531

Website: https://staff.hu.edu.jo/default.aspx?id=pytjhLqE6Ao=#top

Google Scholar: https://scholar.google.com/citations?user=Bix11zcAAAAJ&hl=en

Education

  • B.S., M.S. University of Jordan
  • Ph.D. Colorado State University

About

Cancer arises from changes in basic cell functions. My research focuses on cellular alternations leading to cancer for a better understanding of its initiation and development. This information can help in creating and improving cancer treatments. The lab different projects focus on: Cell migration, adhesion and metastasis; Mitochondrial function and apoptosis; Cytoskeleton and related proteins; Cell cycle and Anti-tumor drugs screening. The same biological concepts are applied in the lab projects studying male infertility

 

 

Publications

  • Characterization of a Human Neuronal Culture System for the Study of Cofilin-Actin Rod PathologyLUBNA H. Tahtamouni, Sydney Alderfer, Thomas Kuhn, Laurie S. Minamide, Soham Chanda, Michael Ruff, James R. Bamburg Biomedicines, 2023.
  • A novel derivative of picolinic acid induces endoplasmic reticulum stress-mediated apoptosis in human non-small cell lung cancer cells: synthesis, docking study, and anticancer activityAli Abbas, Mahmood, Ammar A. Razzak, LUBNA H. Tahtamouni, Zainab A. Al-Mazaydeh, Majdoleen S. Rammaha, Fatima Alsoubani, Al-bayati, Rheda, I PHARMACIA, 3, 2021.
  • Age of the donor affects the nature of in vitro cultured human dental pulp stem cellsHeba Alzer, Heba Kalbouneh, Firas Alsoleihat, Abu Shahin, Nisreen, Soukaina Ryalat, Mohammad Alsalem, Hazem Alahmad, LUBNA H. Tahtamouni SAUDI DENTAL JOURNAL, 7, 2021.
  • Cofilin and Actin Dynamics: Multiple Modes of Regulation and Their Impacts in Neuronal Development and DegenerationJames R. Bamburg, Laurie S. Minamide, O'Neil P. Wiggan, LUBNA H. Tahtamouni, Thomas B. Kuhn CELLS, 10, 2021.
  • Synthesis, docking study, and in vitro anticancer evaluation of new flufenamic acid derivatives Al-Bayati, Ammar, I, Mahmood, Ammar A. Razzak, Zainab A. Al-Mazaydeh, Majdoleen S. Rammaha, Al-bayati, Rheda, I, Fatima Alsoubani, LUBNA H. Tahtamouni PHARMACIA, 2, 2021.
  • Alu-repeat polymorphism in the tissue plasminogen activator (t-PA) gene, seminal t-PA concentration, and male fertilityLubna Hamid Tahtamouni, Mahmoud Nael Hamdan, Zainab Ali Al-Mazaydeh, Randa Mahmoud Bawadi, Majdoleen Sobhi Rammaha, Ahmad Mohammad Zghoul, Mamoun Ahmad Ahram, Salem Refat Yasin INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE, 8, 2020.
  • Biological activity and apoptotic signaling pathway of C-11-functionalized cephalostatin 1 analoguesMansour M. Nawasreh, Alzyoud, Elham, I, Zainab A. Al-Mazaydeh, Majdoleen S. Rammaha, Salem R. Yasin, LUBNA H. Tahtamouni STEROIDS, 2020.
  • SYNTHESIS AND CYTOTOXIC ACTIVITY OF SOME NEW BIPYRAZOLE DERIVATIVESBader A. Salameh, Kayed A. Abu-Safieh, Islam S. AL-Aqrabawi, Fatima Alsoubani, LUBNA H. Tahtamouni HETEROCYCLES, 2, 2020.
  • Cetyl-alcohol-reinforced hollow fiber solid/liquid-phase microextraction and HPLC-DAD analysis of ezetimibe and simvastatin in human plasma and urineNabil N. AL-Hashimi, Rand O. Shahin, Aqeel N. AL-Hashimi, Al Ajeal, Ajeal M., LUBNA H. Tahtamouni, Chanbasha Basheer BIOMEDICAL CHROMATOGRAPHY, 2, 2019.
  • Molecular Regulation of Cancer Cell Migration, Invasion, and MetastasisLUBNA H. Tahtamouni, Mamoun Ahram, Jennifer Koblinski, Christian Rolfo ANALYTICAL CELLULAR PATHOLOGY, 2019.
  • Alu DNA Polymorphism of Human Tissue Plasminogen Activator (tPA) Gene in Diabetic Jordanian PatientsS R. Yasin, H H. AlHawari, A A. Alassaf, M M. Khadra, Z A. Al-Mazaydeh, A F. Al-Emerieen, LUBNA H. Tahtamouni Iranian biomedical journal, 6, 2019.
  • Cephalostatin 1 analogues activate apoptosis via the endoplasmic reticulum stress signaling pathwayLUBNA H. Tahtamouni, Mansour M. Nawasreh, Zainab A. Al-Mazaydeh, Rema A. Al-Khateeb, Reem N. Abdellatif, Randa M. Bawadi, James R. Bamburg, Salem R. Yasin EUROPEAN JOURNAL OF PHARMACOLOGY, 2018.
  • The cellular and molecular effects of the androgen receptor agonist, Cl-4AS-1, on breast cancer cellsMamoun Ahram, Ebtihal Mustafa, Abu Hammad, Shatha, Mariam Alhudhud, Randa Bawadi, LUBNA H. Tahtamouni, Faisal Khatib, Malek Zihlif ENDOCRINE RESEARCH, 3, 2018.
  • Inhibitory effect of Taraxacum officinale L (Compositae) aqueous root extract on spermatogenesisLUBNA H. Tahtamouni, Reem N. Abdellatif, Rema A. Al-Khateeb, Zainab A. Al-Mazaydeh, Salem R. Yasin, Samer I. Al-Gharabli, Ali Z. Elkarmi TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH, 1, 2017.
  • Anti-spermatogenic activities of Taraxacum officinale whole plant and leaves aqueous extractsLubna Hamid Tahtamouni, Rema Ahmad Al-Khateeb, Reem Nasser Abdellatif, Zainab Ali Al-Mazaydeh, Salem Refaat Yasin, Samer Al-Gharabli, Ali Zuhair Elkarmi VETERINARY RESEARCH FORUM, 2, 2016.
  • Human chorionic gonadotropin cutoff value determined by receiver operating characteristic curve analysis is useful but not absolute for determining pregnancy outcomesMaysa M. Khadra, Mazen A. Freij, Muataz Q. Al-Ramahi, Abdullah Y. Al-Jamal, Fida M. Thekrallah, LUBNA H. Tahtamouni MIDDLE EAST FERTILITY SOCIETY JOURNAL, 2, 2016.
  • Novel Palladium(II) and Platinum(II) Complexes with a Fluoropiperazinyl Based Ligand Exhibiting High Cytotoxicity and Anticancer Activity In VitroKayed A. Abu-Safieh, Adnan S. Abu-Surrah, Hani D. Tabba, Huda A. AlMasri, Randa M. Bawadi, Fadila M. Boudjelal, LUBNA H. Tahtamouni JOURNAL OF CHEMISTRY, 2016.
  • Palladium(II) complexes incorporating phenylazo arylmethine ancillary ligands: Synthesis, spectral and antitumor activityMousa Al-Noaimi, Adnan S. Abu-Surrah, LUBNA H. Tahtamouni ARABIAN JOURNAL OF CHEMISTRY, 2016.
  • Screening for CYP2C19 Gene variants in a healthy Jordanian populationSalem Yasin, LUBNA H. Tahtamouni, Rema Al-Khateeb, Reem Abdellatif, Zainab Al-Mazaydeh, Ala'a Al-Emerieen, Hakam Al-Khateeb, Al-Hakam Al-Hadidi TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH, 12, 2016.
  • 2-deoxy-D-Glucose Synergizes with Doxorubicin or L-Buthionine Sulfoximine to Reduce Adhesion and Migration of Breast Cancer Cells.E H. Mustafa, H T. Mahmoud, M Y. Al-Hudhud, M Y. Abdalla, I M. Ahmad, S R. Yasin, A Z. Elkarmi, LUBNA H. Tahtamouni Asian Pacific journal of cancer prevention : APJCP, 8, 2015.
  • Genomic integrity of the Y chromosome sequence-tagged-sites in infertile and Down syndrome Jordanian males.S R. Yasin, LUBNA H. Tahtamouni, N S. Najeeb, N M. Issa, Z A. Al-Mazaydeh, A A. Alfaouri Andrologia, 7, 2014.
  • Feasibility of collecting umbilical cord blood in jordan and the effect of maternal and neonatal factors on hematopoietic stem cell content.A A. Hussein, R M. Bawadi, LUBNA H. Tahtamouni, H Frangoul, A Z. Elkarmi Mediterranean journal of hematology and infectious diseases, 1, 2014.
  • Non-overlapping activities of ADF and cofilin-1 during the migration of metastatic breast tumor cells.LUBNA H. Tahtamouni, Alisa E. Shaw, M H. Hasan, S R. Yasin, James R. Bamburg BMC cell biology, 2013.
  • Dandelion (Taraxacum officinale) decreases male rat fertility in vivoLUBNA H. Tahtamouni, Noor M. Alqurna, Mariam Y. Al-Hudhud, Hameed A. Al-Hajj JOURNAL OF ETHNOPHARMACOLOGY, 1, 2011.
  • Microtubule remodelling is required for the front-rear polarity switch during contact inhibition of locomotionShereen Kadir, Jonathan W. Astin, LUBNA H. Tahtamouni, Paul Taylor Martin, Catherine D. Nobes JOURNAL OF CELL SCIENCE, 15, 2011.
  • Total body glutathione depletion induces oxidative stress and disrupts the immune function in miceMaher Y. Abdalla, Iman M. Hassan, Noor H. Mustafa, LUBNA H. Tahtamouni, Iman M. Ahmad TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY, 1, 2011.
  • 2DG enhances the susceptibility of breast cancer cells to doxorubicinIman M. Ahmad, Ebtihal H. Mustafa, Noor H. Mustafa, LUBNA H. Tahtamouni, Maher Y. Abdalla CENTRAL EUROPEAN JOURNAL OF BIOLOGY, 6, 2010.
  • Prevalence and risk factors for anabolic-androgenic steroid abuse among Jordanian collegiate students and athletes.LUBNA H. Tahtamouni, N H. Mustafa, A A. Alfaouri, I M. Hassan, M Y. Abdalla, S R. Yasin European journal of public health, 6, 2008.
  • Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopeniaBenjamin T. Kile, Athanasia D. Panopoulos, Roslynn A. Stirzaker, Douglas F. Hacking, LUBNA H. Tahtamouni, Tracy A. Willson, Lisa A. Mielke, Katya J. Henley, Jian-Guo Zhang, Ian P. Wicks, William S. Stevenson, Paquita Nurden, Stephanie S. Watowich, Monica J. Justice BLOOD, 7, 2007.